Constipation caused by medicines: Information for patients and carers

 This advice is sourced from Dr Ros Taylor a senior palliative physician

These are some questions I am often asked about constipation and medication.

Which medicines cause constipation?

Many painkillers especially morphine and related medicines such as codeine, tramadol, fentanyl and oxycodone.

Nerve pain medicines such as pregabalin, gabapentin and amitriptyline.

Muscle relaxants such as buscopan and some anti-sickness drugs like cyclizine and ondansetron.

How do these medicines cause constipation?

The main reason that medicines cause constipation is that they slow down bowel transit time (the amount of time it takes for food to pass down through the digestive system).

The longer bowel contents are in the bowel, the drier they get as water is absorbed out of the stools back into the body. 

What are the best treatments for constipation caused by medication?

You need treatments to speed up the bowel (e.g. senna or picosulfate) whilst taking medication that slows the bowel down.

You may need something to soften the stools (e.g. laxido, movicol or docusate).

If you have always had a medication for constipation that works well for you this is the one to use initially.

What are the other approaches that can help?

Remember that drinking enough fluid is crucial for softening stools.

Eating foods which contain fibre also helps (e.g. fruit, vegetables, wholegrains).

If the stool is really hard to push out, then gylcerine suppositories may help soften the stool and make it easier to pass.

Good toilet posture can be very helpful. This webpage from Macmillan explains how sitting in the right position on the toilet can help.

If constipation improves can I stop taking laxatives?

It is recommended to always use regular laxatives whilst taking regular medication, particularly strong painkillers.

 

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Published 31st July 2021

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W. https://www.stjohnshospice.org.uk/our-care/inpatient-care

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Hospices

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Community Palliative Care Team - based at Meadow House Hospice

T. 020 8967 5179

W. https://www.lnwh.nhs.uk/meadow-house-hospice/#community-palliative-care-team

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Referral form for clinician use only.

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Community Palliative Care Team - based at St. John's Hospice
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T. 020 7806 4040

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T. 020 7787 1062

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Harlington Hospice

T. 020 8759 0453

W. https://www.harlingtonhospice.org/

Harlington Hospice provides a wide range of palliative care services to the residents of Hillingdon and surrounding areas.

The Hospice hosts a Wellbeing Service (shared with Michael Sobell Hospice), complementary therapies, counselling, lymphoedema service and the CABS team supporting children and adolescents.

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Meadow House Hospice Inpatient Unit

T. 0208 967 5179

W. http://meadowhouse.lnwh.nhs.uk

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The hospice has a 15 bedded inpatient unit supported by a team of dedicated staff providing 24/7 specialist support to patients and their family members. Patients with a progressive life limiting illness can be admitted for symptom management or end of life care.

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Please contact the hospice Monday to Friday 8.30am to 4.30pm and during the weekend 9.00am to 5.00pm on 0208 242 5817.

There is a 24 hour telephone support line to the hospice ward on 0208 967 5597.

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Referral form for clinician use only.

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Michael Sobell Hospice Inpatient Unit (MSH)
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Michael Sobell Hospice Inpatient Unit (MSH)

T. 020 8106 9201

W. https://www.harlingtonhospice.org/michael-sobell-house/

The Michael Sobell Hospice provides a range of palliative services for people with advancing illness.

The Hospice has 10 beds in its refurbished inpatient unit and looks after people with complex symptoms as well as those close to the end of their life.

Many people have a short admission and get back home agian.

The Hospice hosts the 24 hour Hillingdon advice line  on 020 3824 1268

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Please use the referral form below.

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Royal Trinity Hospice
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Royal Trinity Hospice

T. 0207 787 1062

W. https://www.royaltrinityhospice.london/

Royal Trinity Hospice provides palliative care services to the residents of Hammersmith and Fulham, Central London and West London.

There is a 24 hour, 7 days a week clinical advice line and OOH access to the on-call consultant.

Referral form for clinician use only.

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St John's Hospice at Home
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St John's Hospice at Home

T. 020 7806 4027

St. John's Hospice provides palliative care services to the residents of Brent and Westminster.

Telephone response will be received within 2 hours.

Inclusions are: Terminal care last 2 weeks of life, 24 hour, admission avoidance, facilitated discharge and respite care escorting a patient.

Referral form for clinician use only.

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St John's Hospice Inpatient unit
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St John's Hospice Inpatient unit

T. 020 7806 4040 / 07725 258767

W. https://www.stjohnshospice.org.uk/our-care/inpatient-care

St. John's Hospice provides inpatient palliative care services to the residents of Brent, Central London and West London.

This is an inpatient unit with 18 beds

Please contact for admissions for advice and Community Specialist Palliative Care.

The office hours are Monday to Friday 8.30am to 4.30pm. Referrals received in the morning are triaged the same afternoon, and those received in the afternoon are triaged the following working day.

If urgent, please follow up the referral by calling us on 020 7806 4040. Out of hours, urgent referrals will be discussed with the consultant on call.

Referral form for clinician use only.

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St Luke's Hospice at Home
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St Luke's Hospice at Home

T. 0208 382 8020 / 8050

St. Lukes Hospice@Home provides palliative care services to the residents of North Brent and Harrow. Respite and bridging packages of care are available for end of life patients.

Please contact the team between Monday to Saturday 9.00am to 5.00pm.

The email can be used for fast track referrals.

Referral form for clinician use only.

Community Specialist Palliative Care Referral Form V4.2 (DOCX)

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