Anxiety towards the end of life: Information for clinicians

This advice is sourced from Dr Heather Wells, Clinical Psychologist and Dr Ros Taylor a senior palliative physician

Anxiety is very common in advancing illness. 

For many people death is a taboo subject. Unexpressed fears about the end of life can worsen anxiety, affect quality of life and impact a persons ability to have a good ending.

Leaning in to exploring individual worries is key and requires brave empathic communication. Patients can feel overwhelmed and the conversations can't be rushed. Depending on your clinical setting it may require several appointments to explore, and your patient should control the pace.

Causes of anxiety can range from the practical to the spiritual. Some of these worries can be resolved and others can be shared, explored and often become more tolerable over time. 

Discussing fears and worries often leads on to identifing goals of care, and can help people to plan how they want to live.

Common worries we see in practice

Pain – people may worry about dying in pain; those with cancer may worry that new pain is a sign of the cancer spreading

End of treatment – people may struggle to adjust when active treatment of an illness stops e.g. chemotherapy

Being isolated from friends and family

Family worries – for example, worrying about being a burden 

Legal, financial and housing worries - often not explored by clinicians

Spiritual distress

The process of dying - this can be gently explained

Assessment of severity

A validated tool such as GAD-7 can be helpful to guide treatment

Non pharmacological treatment

Recommended book: Free yourself from Death Anxiety. A CBT Self-Help Guide for a Fear of Death and Dying. Menzies and Veale 2022

Pharmacological treatment
  • Benzodiazepines e.g. long acting diazepam or clonazepam (half life 30 hours) or short acting lorazepam (half life 12 hours)
  • SSRIs such as citalopram, escitalopram or sertraline
  • Atypical antidepressants e.g. mirtazapine or pregabalin

In palliative practice we have a lower threshold for prescribing anxiolytics and often use benzodiazepines (BDZs) to support titration of antidepressants. BDZs are a useful short term intervention to reduce severe anxiety so that patients can engage with other non pharmacological strategies

Recommended Resources

Oxford Textbook of Palliative Care

Published 1st January 2019

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