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Identification of end stage heart failure: Information for clinicians

The following are triggers to consider a referral to palliative care in heart failure:

Clinical symptoms and and signs:

  • Worsening breathlessness at rest and often at night when lying flat (New York Heart Association class IV)
  • Increasing oedema limiting function and requiring increasing diuretics
  • Frequent admissions to hospital with fluid overload
  • Reduced mobility, weight loss, poor sleep and reduced appetite (cardiac cachexia) 
  • Nocturnal dyspnoea

Metabolic indicators:

  • Progressive deterioration in estimated glomerular filtration rate (eGFR) , creatinine and potassium levels
  • Hypotension limiting the use of drug treatments
  • Serial increases in Beta natriuretic peptide (BNP)
  • Albumin as a marker of cachexia 

Why is it important to identify

  • As an opportunity to discuss future care and wishes
  • Plans to avoid admission e.g. flexible PRN diuretic plans - oral or subcutaneous
  • Referral to palliative care
  • Prioritise symptom relief for breathlessness, oedema, insomnia and nausea
  • Diuretic review e.g. switching from furosemide to bumetanide which is better absorbed if extensive oedema present (40mg PO furosemide is equivalent to 1mg PO bumetanide)
  • ICD deactivation if relevant

Recommended Resources

NICE CKS - Heart failure - chronic

Published 1st September 2025

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Heart failure services

British Heart Foundation
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British Heart Foundation

T. 0300 330 3322

W. https://www.bhf.org.uk/

The British Heart Foundation provides information on heart and circulatory diseases.

Patients and carers can get support through the online support groups and communities, advice and guidance about heart and circulatory conditions and managing risk factors.

Pumping Marvellous - Heart Failure Charity UK
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Pumping Marvellous - Heart Failure Charity UK

W. https://pumpingmarvellous.org/

Pumping Marvellous offers support to help people live well with heart failure, to recognise the early symptoms and self-interventions through their community hub.

Palliative care advice lines

NCL Palliative Advice Team
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NCL Palliative Advice Team

T. 020 8152 3252

W. https://northlondonhospice.org/get-support/out-of-hours-telephone-advice

The North Central London Palliative Advice Team is a telephone service providing palliative care patients, families, carers, and healthcare professionals (in NCL ICS boroughs) with out of hours advice and support.

The telephone service is available 8.00pm to 8.00am, seven days a week.

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